Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.1
USERS' SCORE
Good
Based on 9 Reviews
8.2
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Vitamin B12 (as Methylcobalamin)
1,500 mcg
62500%
Top Medical Research Studies
9
We conducted a study to investigate the effects of mecobalamin, a form of vitamin B12, on carpal tunnel syndrome (CTS) in stroke patients. Our research involved a group of 135 stroke patients, with 67 receiving 1,500 micrograms of mecobalamin daily for two years, while the other 68 patients did not receive any treatment.
Remarkably, we found that many stroke patients exhibited greater abnormality in the nerve function of their nonparetic side (the side of the body not affected by stroke) compared to the hemiparetic side (the affected side). Before treatment began, nearly a third of both groups met the criteria for CTS.
Over the two years, those who took mecobalamin showed a significant improvement in sensory nerve responses when compared to the untreated group. We observed that even though both sensory and motor nerve functions improved, the sensory nerve functions in the treated patients improved more noticeably. Importantly, there were no reported side effects from the treatment, suggesting that oral mecobalamin could be a safe and beneficial option for managing CTS, especially in stroke patients.
Remarkably, we found that many stroke patients exhibited greater abnormality in the nerve function of their nonparetic side (the side of the body not affected by stroke) compared to the hemiparetic side (the affected side). Before treatment began, nearly a third of both groups met the criteria for CTS.
Over the two years, those who took mecobalamin showed a significant improvement in sensory nerve responses when compared to the untreated group. We observed that even though both sensory and motor nerve functions improved, the sensory nerve functions in the treated patients improved more noticeably. Importantly, there were no reported side effects from the treatment, suggesting that oral mecobalamin could be a safe and beneficial option for managing CTS, especially in stroke patients.
Read More
8
Methylcobalamin shows promise for carpal tunnel
We explored the potential benefits of vitamin B12, specifically methylcobalamin, in treating carpal tunnel syndrome. This vitamin is essential for maintaining the nervous system and has shown promise in easing symptoms associated with peripheral nerve disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Read More
9
We explored the clinical effects of a treatment approach involving vitamin B12 for patients with carpal tunnel syndrome. Our study included a total of 60 patients divided into two groups: one receiving needle Dao treatment and the other treated with a combination of a brace and vitamin B12, among other medications.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
Read More
Most Useful Reviews
9
Numbness alleviated
10 people found this helpful
I highly recommend it! After experiencing numbness at the base of my thumb, I discovered it was Carpal Tunnel Syndrome. Methylcobalamin was prescribed, and after researching, I found that vitamin B12 was the primary component. I took one capsule with dinner, along with a support band, and the numbness faded after three consecutive days. Although I still feel a little uncomfortable, it is improving daily, and I will continue taking it.
Read More
9
Pain relief achieved
9 people found this helpful
Seven years ago, I developed Carpal Tunnel Syndrome from a job change and was treated for about two months with Methycobal 500, which effectively cured me. Recently, while gardening, I felt pain around my thumbs again, so I started taking this supplement, which resembles Methycobal. It has provided similar pain relief effects, and I intend to keep taking it.
Read More
10
Significant improvement
Excellent! Thanks to this, my Carpal Tunnel Syndrome condition has greatly improved. I used to wake up with numbness, and now it feels much easier to recover. I’m truly grateful for it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.1
- All Researches
9
We explored the clinical effects of a treatment approach involving vitamin B12 for patients with carpal tunnel syndrome. Our study included a total of 60 patients divided into two groups: one receiving needle Dao treatment and the other treated with a combination of a brace and vitamin B12, among other medications.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
Read More
9
We explored the effects of a combination treatment involving uridine monophosphate, folic acid, and vitamin B12 on patients suffering from carpal tunnel syndrome, the most prevalent form of peripheral entrapment neuropathy. In our open-label study, 48 patients were given a daily capsule containing these three components over a two-month period.
By using the Pain DETECT questionnaire, we aimed to assess any improvements in pain levels and related symptoms. The results were encouraging, with overall pain scores dropping significantly—from an average of 17.3 to 10.3. Notably, many participants were able to either stop or reduce their use of analgesics and anti-inflammatory medications during the study.
Despite the positive findings, it's essential to highlight that the benefits observed were attributed to the combination of substances and not solely to vitamin B12. Therefore, to better understand the role of each component, particularly vitamin B12, further well-structured and larger randomized controlled trials are needed.
By using the Pain DETECT questionnaire, we aimed to assess any improvements in pain levels and related symptoms. The results were encouraging, with overall pain scores dropping significantly—from an average of 17.3 to 10.3. Notably, many participants were able to either stop or reduce their use of analgesics and anti-inflammatory medications during the study.
Despite the positive findings, it's essential to highlight that the benefits observed were attributed to the combination of substances and not solely to vitamin B12. Therefore, to better understand the role of each component, particularly vitamin B12, further well-structured and larger randomized controlled trials are needed.
Read More
9
We conducted a study to investigate the effects of mecobalamin, a form of vitamin B12, on carpal tunnel syndrome (CTS) in stroke patients. Our research involved a group of 135 stroke patients, with 67 receiving 1,500 micrograms of mecobalamin daily for two years, while the other 68 patients did not receive any treatment.
Remarkably, we found that many stroke patients exhibited greater abnormality in the nerve function of their nonparetic side (the side of the body not affected by stroke) compared to the hemiparetic side (the affected side). Before treatment began, nearly a third of both groups met the criteria for CTS.
Over the two years, those who took mecobalamin showed a significant improvement in sensory nerve responses when compared to the untreated group. We observed that even though both sensory and motor nerve functions improved, the sensory nerve functions in the treated patients improved more noticeably. Importantly, there were no reported side effects from the treatment, suggesting that oral mecobalamin could be a safe and beneficial option for managing CTS, especially in stroke patients.
Remarkably, we found that many stroke patients exhibited greater abnormality in the nerve function of their nonparetic side (the side of the body not affected by stroke) compared to the hemiparetic side (the affected side). Before treatment began, nearly a third of both groups met the criteria for CTS.
Over the two years, those who took mecobalamin showed a significant improvement in sensory nerve responses when compared to the untreated group. We observed that even though both sensory and motor nerve functions improved, the sensory nerve functions in the treated patients improved more noticeably. Importantly, there were no reported side effects from the treatment, suggesting that oral mecobalamin could be a safe and beneficial option for managing CTS, especially in stroke patients.
Read More
8
Methylcobalamin shows promise for carpal tunnel
We explored the potential benefits of vitamin B12, specifically methylcobalamin, in treating carpal tunnel syndrome. This vitamin is essential for maintaining the nervous system and has shown promise in easing symptoms associated with peripheral nerve disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Read More
7
Vitamin B12 benefits unclear in CTS
We aimed to understand how vitamin B12 affects carpal tunnel syndrome (CTS) treatment. While vitamin B12 was included as part of a broader conservative treatment strategy, the specifics of its isolated effectiveness remain unclear.
As we explored the statistics gathered, we observed that vitamin B12 was recommended along with other treatments like nonsteroidal anti-inflammatory drugs and a neutral wrist splint. However, the data did not provide strong evidence that vitamin B12 alone offers significant benefits for CTS beyond these combined treatments.
Therefore, while some patients may find relief using vitamin B12 as part of their regimen, we need more focused research to highlight its true impact on CTS symptoms, separate from other interventions.
As we explored the statistics gathered, we observed that vitamin B12 was recommended along with other treatments like nonsteroidal anti-inflammatory drugs and a neutral wrist splint. However, the data did not provide strong evidence that vitamin B12 alone offers significant benefits for CTS beyond these combined treatments.
Therefore, while some patients may find relief using vitamin B12 as part of their regimen, we need more focused research to highlight its true impact on CTS symptoms, separate from other interventions.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Numbness alleviated
10 people found this helpful
I highly recommend it! After experiencing numbness at the base of my thumb, I discovered it was Carpal Tunnel Syndrome. Methylcobalamin was prescribed, and after researching, I found that vitamin B12 was the primary component. I took one capsule with dinner, along with a support band, and the numbness faded after three consecutive days. Although I still feel a little uncomfortable, it is improving daily, and I will continue taking it.
Read More
9
Pain relief achieved
9 people found this helpful
Seven years ago, I developed Carpal Tunnel Syndrome from a job change and was treated for about two months with Methycobal 500, which effectively cured me. Recently, while gardening, I felt pain around my thumbs again, so I started taking this supplement, which resembles Methycobal. It has provided similar pain relief effects, and I intend to keep taking it.
Read More
10
Significant improvement
Excellent! Thanks to this, my Carpal Tunnel Syndrome condition has greatly improved. I used to wake up with numbness, and now it feels much easier to recover. I’m truly grateful for it.
Read More
10
Complete recovery
I’ve regularly taken this vitamin B12 (methylcobalamin type) due to wrist pain and Carpal Tunnel Syndrome-like symptoms. After about a month, the pain and numbness nearly vanished. Although it might have healed naturally, three months later, I’m completely cured. B12 benefits both the eyes and brain, making it essential for me.
Read More
9
Eases condition
This vitamin B12 works wonderfully, assisting with my Carpal Tunnel Syndrome and maintaining my condition. The capsule size is quite agreeable, making it easy to take daily over several months.
Read More
Frequently Asked Questions
9
Numbness alleviated
10 people found this helpful
I highly recommend it! After experiencing numbness at the base of my thumb, I discovered it was Carpal Tunnel Syndrome. Methylcobalamin was prescribed, and after researching, I found that vitamin B12 was the primary component. I took one capsule with dinner, along with a support band, and the numbness faded after three consecutive days. Although I still feel a little uncomfortable, it is improving daily, and I will continue taking it.
6
Nausea improved
7 people found this helpful
For my Carpal Tunnel Syndrome, I take one capsule each morning and evening. I used to wake up with numbness and felt this during the day as well. After about two weeks of taking it, my nausea diminished. I make an effort to perform light stretches and plan to continue this regimen.
10
Complete recovery
I’ve regularly taken this vitamin B12 (methylcobalamin type) due to wrist pain and Carpal Tunnel Syndrome-like symptoms. After about a month, the pain and numbness nearly vanished. Although it might have healed naturally, three months later, I’m completely cured. B12 benefits both the eyes and brain, making it essential for me.
10
Significant improvement
Excellent! Thanks to this, my Carpal Tunnel Syndrome condition has greatly improved. I used to wake up with numbness, and now it feels much easier to recover. I’m truly grateful for it.
2
Ineffective for relief
2 people found this helpful
I wish I could provide a positive review, but these simply do not work for treating my Carpal Tunnel Syndrome. I have previously taken B12 for this condition with great results, but these capsules failed to produce any effect at all. I won’t be purchasing them again. However, I recognise that everyone is different, so they may work for someone else.
7.5
Numbness reduced
3 people found this helpful
I’m not fond of vitamin complexes as they obscure individual vitamin dosages. I prefer taking specific vitamins separately, like B12. I developed Carpal Tunnel Syndrome from poor working habits. My fingers were extremely numb and painful. After considering surgery or finding a less invasive route, I incorporated wrist exercises and realised I was deficient in vitamin B12. This adjustment has helped; my fingers are no longer numb, thanks to the combination of exercises and vitamins.
7
Vitamin B12 benefits unclear in CTS
We aimed to understand how vitamin B12 affects carpal tunnel syndrome (CTS) treatment. While vitamin B12 was included as part of a broader conservative treatment strategy, the specifics of its isolated effectiveness remain unclear.
As we explored the statistics gathered, we observed that vitamin B12 was recommended along with other treatments like nonsteroidal anti-inflammatory drugs and a neutral wrist splint. However, the data did not provide strong evidence that vitamin B12 alone offers significant benefits for CTS beyond these combined treatments.
Therefore, while some patients may find relief using vitamin B12 as part of their regimen, we need more focused research to highlight its true impact on CTS symptoms, separate from other interventions.
As we explored the statistics gathered, we observed that vitamin B12 was recommended along with other treatments like nonsteroidal anti-inflammatory drugs and a neutral wrist splint. However, the data did not provide strong evidence that vitamin B12 alone offers significant benefits for CTS beyond these combined treatments.
Therefore, while some patients may find relief using vitamin B12 as part of their regimen, we need more focused research to highlight its true impact on CTS symptoms, separate from other interventions.
9
We explored the clinical effects of a treatment approach involving vitamin B12 for patients with carpal tunnel syndrome. Our study included a total of 60 patients divided into two groups: one receiving needle Dao treatment and the other treated with a combination of a brace and vitamin B12, among other medications.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
The results showed improvements in nerve function for both groups. However, it's important to note that while vitamin B12 was part of the treatment in the control group, we cannot definitively say how much it contributed to the overall results because it was used alongside other treatments.
The findings indicate that while vitamin B12 is included in the conventional treatment approach, its isolated effect remains unclear within this study's context. Therefore, we recommend further studies to better understand its effectiveness in managing carpal tunnel syndrome.
8
Methylcobalamin shows promise for carpal tunnel
We explored the potential benefits of vitamin B12, specifically methylcobalamin, in treating carpal tunnel syndrome. This vitamin is essential for maintaining the nervous system and has shown promise in easing symptoms associated with peripheral nerve disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
Through various studies, including in vitro and in vivo research, it was observed that methylcobalamin plays a role in neuron health by supporting DNA and protein functions, and promoting the growth of nerve fibers. Furthermore, it appears to inhibit cell death in nerve cells, which could help alleviate some of the discomfort experienced by individuals with carpal tunnel syndrome.
Patients treated with high doses of methylcobalamin reported improvements in their symptoms, along with positive changes in nerve function. This suggests that high-dose methylcobalamin may hold significant value in addressing issues related to nerve damage or dysfunction.
Overall, as we continue to investigate methylcobalamin's mechanisms and effects, it may pave the way for more effective treatments for carpal tunnel syndrome and potentially other nerve-related disorders.
4
Vitamin B12's limited effectiveness observed
In our study, we aimed to assess the effectiveness of vitamin B12 as part of a multivitamin treatment for individuals suffering from carpal tunnel syndrome (CTS). We compared two groups: one receiving a combination of alpha-lipoic acid and gamma-linolenic acid, and the other taking a multivitamin preparation containing vitamin B1, B6, and B12.
Over the course of 90 days, we monitored the participants' symptoms using questionnaires and conducted electro-myography to evaluate nerve function. While we noted a slight improvement in symptoms among those taking vitamins, it was not as pronounced as in the alpha-lipoic acid and gamma-linolenic acid group.
Additionally, the multivitamin group experienced a worsening of functional scores, indicating that the vitamin B12 component did not provide significant benefits for CTS. Thus, our findings suggest that vitamin B12, while included in a multivitamin, may not be effective for improving the symptoms and functionality in carpal tunnel syndrome patients.
Over the course of 90 days, we monitored the participants' symptoms using questionnaires and conducted electro-myography to evaluate nerve function. While we noted a slight improvement in symptoms among those taking vitamins, it was not as pronounced as in the alpha-lipoic acid and gamma-linolenic acid group.
Additionally, the multivitamin group experienced a worsening of functional scores, indicating that the vitamin B12 component did not provide significant benefits for CTS. Thus, our findings suggest that vitamin B12, while included in a multivitamin, may not be effective for improving the symptoms and functionality in carpal tunnel syndrome patients.
4
We explored the effectiveness of different treatments for carpal tunnel syndrome, focusing specifically on vitamin B12's role. In our study, we looked at 61 patients with a total of 99 affected hands and compared five treatment approaches. These included the use of vitamins B6 and B12, steroid injections, hand splints, and combinations of these methods.
After assessing each patient with electrodiagnostic studies before treatment and again after one and two months, we found that treatments involving hand splinting, local steroid injections, and combination therapies delivered better results when it came to sensory nerve conduction studies. Notably, vitamin B12 used alone did not show substantial benefits. In fact, the combined treatments that included steroid injections appeared to work faster and more effectively for relieving symptoms.
Overall, our findings suggest that relying solely on vitamin B12 for carpal tunnel syndrome is not sufficient. Instead, a combination approach, particularly involving steroid injections and splinting, seems to be a more effective conservative treatment option for this condition.
After assessing each patient with electrodiagnostic studies before treatment and again after one and two months, we found that treatments involving hand splinting, local steroid injections, and combination therapies delivered better results when it came to sensory nerve conduction studies. Notably, vitamin B12 used alone did not show substantial benefits. In fact, the combined treatments that included steroid injections appeared to work faster and more effectively for relieving symptoms.
Overall, our findings suggest that relying solely on vitamin B12 for carpal tunnel syndrome is not sufficient. Instead, a combination approach, particularly involving steroid injections and splinting, seems to be a more effective conservative treatment option for this condition.
References
- Kokubo R, Kim K. [Carpal Tunnel Syndrome:Diagnosis and Treatment]. No Shinkei Geka. 2021;49:1306. doi:10.11477/mf.1436204516
- Zhang KY, Yang Y, Xu SW, Shou Y, Jiang HR, et al. [A case-control study on the treatment of carpal tunnel syndrome with needle Dao]. Zhongguo Gu Shang. 2018;31:497. doi:10.3969/j.issn.1003-0034.2018.06.002
- Negrão L, Nunes P. Uridine monophosphate, folic acid and vitamin B12 in patients with symptomatic peripheral entrapment neuropathies. Pain Manag. 2016;6:25. doi:10.2217/pmt.15.60
- Tanaka H. [Old or new medicine? Vitamin B12 and peripheral nerve neuropathy]. Brain Nerve. 2013;65:1077.
- Zhang CY, Wang YX. [Observation on therapeutic effects of acupuncture combined with TDP irradiation and chinese herbal steaming and washing therapy for treatment of carpal tunnel syndrome in early stage]. Zhongguo Zhen Jiu. 2009;29:708.
- Di Geronimo G, Caccese AF, Caruso L, Soldati A, Passaretti U. Treatment of carpal tunnel syndrome with alpha-lipoic acid. Eur Rev Med Pharmacol Sci. 2009;13:133.
- Sato Y, Honda Y, Iwamoto J, Kanoko T, Satoh K. Amelioration by mecobalamin of subclinical carpal tunnel syndrome involving unaffected limbs in stroke patients. J Neurol Sci. 2005;231:13.
- Wu SF, Chan RC, Hsu TC. [Electrodiagnostic evaluation of conservative treatment in carpal tunnel syndrome]. Zhonghua Yi Xue Za Zhi (Taipei). 1991;48:125.
